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Article

Leptin and leptin receptor gene polymorphisms and depression treatment response.

Acta neuropsychiatrica - 12 Nov 2024

Tavast Ida-Maria, Solismaa Anssi, Lyytikäinen Leo-Pekka, Mononen Nina, Moilanen Eeva, Hämäläinen Mari, Lehtimäki Terho, Kampman Olli

Abstract excerpt

OBJECTIVE: Associations between leptin (LEP) and leptin receptor (LEPR) gene polymorphisms and mood disorders have been found but not yet confirmed in multiple studies. The aim of our study was to study the associations between LEP and LEPR single nucleotide polymorphisms (SNPs) and treatment response of depression. Associations between leptin levels and depression severity were also investigated. METHODS: The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39529327
DOI: 10.1017/neu.2024.43
PMCID: PMC13130323

Genes

LEPR
LEP

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