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Evaluation of the clinical performance of anti-mutated citrullinated vimentin antibody and 14-3-3 eta testing in rheumatoid arthritis.

Clinical chemistry and laboratory medicine - 26 Mar 2025

Nelson Heather A, Martins Thomas B, Saadalla Abdulrahman, Nandakumar Vijayalakshmi

Abstract excerpt

OBJECTIVES: Early rheumatoid arthritis (RA) detection is crucial for improving patient prognosis. Anticyclic citrullinated peptide antibodies (anti-CCP) and rheumatoid factors (RF) support RA diagnosis but are undetectable in ∼20 % of cases. Recently, antibodies against mutated citrullinated vimentin (anti-MCV) and detection of 14-3-3 eta have emerged with implications for preclinical RA diagnosis and monitoring...

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Identifiers

PMID: 39501963
DOI: 10.1515/cclm-2024-1112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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