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Article

Completely non-invasive prediction of IDH mutation status based on preoperative native CT images.

Scientific reports - 5 Nov 2024

Musigmann Manfred, Bilgin Melike, Bilgin Sabriye Sennur, Krähling Hermann, Heindel Walter, Mannil Manoj

Abstract excerpt

The isocitrate dehydrogenase (IDH) mutation status is one of the most important markers according to the 2021 WHO classification of CNS tumors. Preoperatively, this information is usually obtained based on invasive biopsies, contrast-enhanced MR images or PET images generated using radioactive tracers. However, the completely non-invasive determination of IDH mutation status using routinely acquired preoperative...

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PMID: 39501053
DOI: 10.1038/s41598-024-77789-6
PMCID: PMC11538254

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