Article
Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality.
Human genetics - 1 Mar 2021
Adewuyi Emmanuel O, Mehta Divya, Sapkota Yadav, Auta Asa, Yoshihara Kosuke, Nyegaard Mette, Griffiths Lyn R, Montgomery Grant W, Chasman Daniel I, Nyholt Dale R
Abstract excerpt
Evidence from observational studies indicates that endometriosis and depression often co-occur. However, conflicting evidence exists, and the etiology as well as biological mechanisms underlying their comorbidity remain unknown. Utilizing genome-wide association study (GWAS) data, we comprehensively assessed the relationship between endometriosis and depression. Single nucleotide polymorphism effect concordance...
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