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Article

Unearthing a Prostate Cancer cfDNA Signature that "Stems" from AR Alterations.

Clinical cancer research : an official journal of the American Association for Cancer Research - 6 Jan 2025

Nawfal Rashad, El Hajj Chehade Razane, Berchuck Jacob E

Abstract excerpt

Androgen receptor alterations portend a poor prognosis in patients with advanced prostate cancer. A recent study identified a stemness signature enriched in cell-free DNA from androgen receptor-altered patients, associated with worse outcomes. These findings highlight the potential of epigenomic liquid biopsy tools to discover novel clinically relevant tumor molecular subtypes. See related article by Chauhan et...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39495177
DOI: 10.1158/1078-0432.CCR-24-2849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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