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Article

Polycystic ovary syndrome and insulin resistance: A focus on pathogenesis, risk factors, and therapeutic strategies.

Journal of reproductive immunology - 1 Aug 2026

Singla Jyoti, Yadav Shubhi, Gayen Jiaur R

Abstract excerpt

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder characterized by significant reproductive and metabolic complications. Insulin resistance (IR) plays a central role in the pathophysiology of PCOS and contributes to several associated metabolic abnormalities. This review highlights the key mechanisms underlying PCOS, including IR, hyperandrogenism, cardiovascular disease, gut microbiota dysbiosis,...

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Dysbiosis
Gastrointestinal Microbiome
Hyperandrogenism
Metformin
Polycystic Ovary Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Androgen

Steroid 17-alpha-Hydroxylase

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PMID: 42531755
DOI: 10.1016/j.jri.2026.104943

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AR
FSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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