Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel HLA-DQB1, DQA1, DPA1 and DPB1 alleles identified in the Australian New South Wales tissue typing laboratory.

Human immunology - 1 Nov 2024

Velickovic Marija, Turner Thomas R, Cooper Michael A, Hopper Sebastian J F

Abstract excerpt

Introduction of NGS into clinical histocompatibility laboratories has greatly increased the frequency of novel HLA allele discovery. We identified 9 DQA1, 7 DQB1, 8 DPA1 and 2 DPB1 novel alleles over the last 2 years. 92% (24 of 26) differed from their closest allele by single nucleotide substitutions detected in coding regions and 84% (22 of 26) contained polymorphism outside of exon 2. Identification of novel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Testing

Share to HLA-DP alpha-Chains

Share to HLA-DP beta-Chains

Share to HLA-DQ alpha-Chains

Share to HLA-DQ beta-Chains

Share to New South Wales

Source

Identifiers

PMID: 39488996
DOI: 10.1016/j.humimm.2024.111171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel HLA-DQB1, DQA1, DPA1 and DPB1 alleles identified in the Australian New South Wales tissue typing laboratory.PMID 39488996Read ↗

NGS and HLA: The long road ahead.Semantic proximity Read ↗

The novel HLA class II allele, DPB1*1284:01, identified using next-generation sequencing.Semantic proximity Read ↗

Fifty novel HLA-DPB1 alleles identified in a UK cohort of unrelated hematopoietic cell donors and recipients.Semantic proximity Read ↗

Novel alleles in the era of next-generation sequencing-based HLA typing calls for standardization and policySemantic proximity Read ↗

Characterisation of 41 Novel HLA Alleles Identified in UK Haematopoietic Cell Transplant Donors.Semantic proximity Read ↗

Four novel HLA class II alleles identified using next-generation sequencing.Semantic proximity Read ↗

Widespread non-coding polymorphism in HLA class II genes of International HLA and Immunogenetics Workshop cell lines.Semantic proximity Read ↗

Detection of 549 new HLA alleles in potential stem cell donors from the United States, Poland and Germany.Semantic proximity Read ↗

Identification of the novel HLA-DPA1*01:03:43 allele resulting from an intralocus recombination involving the DPA1*04:01:01:03 and DPA1*01:03:01:27 alleles sequenced by Next Generation Sequencing (NGS).Semantic proximity Read ↗

Three hundred and seventy-two novel HLA class II alleles identified in potential hematopoietic stem cell donors from Germany, the United States, and Poland.Semantic proximity Read ↗

Sequencing-based typing identifies novel alleles due to single nucleotide polymorphisms in 'conserved' regions.Semantic proximity Read ↗

Identification of two novel alleles, HLA-A*02:01:193 and -DQA1*02:17, in Greek individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.