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Cumulative effects of mutation accumulation on mitochondrial function and fitness.

Mitochondrion - 1 Jan 2025

Paquin Frédérique, Cristescu Melania E, Blier Pierre U, Lemieux Hélène, Dufresne France

Abstract excerpt

The impact of mutations on the mitochondria deserves specific interest due to the crucial role played by these organelles on numerous cellular functions. This study examines the effects of repeated bottlenecks on mitochondrial function and fitness. Daphnia pulex mutation accumulation lines (MA) lines were maintained for over 120 generations under copper and no copper conditions. Following the MA propagation,...

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Copper
Daphnia
DNA Copy Number Variations
DNA, Mitochondrial
Genetic Fitness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation Accumulation

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PMID: 39486563
DOI: 10.1016/j.mito.2024.101976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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