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Article

High mutational rates of large-scale duplication and deletion in Daphnia pulex.

Genome research - 1 Jan 2016

Keith Nathan, Tucker Abraham E, Jackson Craig E, Sung Way, Lucas Lledó José Ignacio, Schrider Daniel R, Schaack Sarah, Dudycha Jeffry L, Ackerman Matthew, Younge Andrew J, Shaw Joseph R, Lynch Michael

Abstract excerpt

Knowledge of the genome-wide rate and spectrum of mutations is necessary to understand the origin of disease and the genetic variation driving all evolutionary processes. Here, we provide a genome-wide analysis of the rate and spectrum of mutations obtained in two Daphnia pulex genotypes via separate mutation-accumulation (MA) experiments. Unlike most MA studies that utilize haploid, homozygous, or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26518480
DOI: 10.1101/gr.191338.115
PMCID: PMC4691751

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