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Subphenotypes of adult-onset diabetes: Data-driven clustering in the population-based KORA cohort.

Diabetes, obesity & metabolism - 1 Jan 2025

Dong Qiuling, Xi Yue, Brandmaier Stefan, Fuchs Markéta, Huemer Marie-Theres, Waldenberger Melanie, Niu Jiefei, Herder Christian, Rathmann Wolfgang, Roden Michael, Koenig Wolfgang, Bönhof Gidon J, Gieger Christian, Thorand Barbara, Peters Annette, Rospleszcz Susanne, Grallert Harald

Abstract excerpt

AIMS: A data-driven cluster analysis in a cohort of European individuals with type 2 diabetes (T2D) has previously identified four subgroups based on clinical characteristics. In the current study, we performed a comprehensive statistical assessment to (1) replicate the above-mentioned original clusters; (2) derive de novo T2D subphenotypes in the Kooperative Gesundheitsforschung in der Region Augsburg (KORA)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39466719
DOI: 10.1111/dom.16022
PMCID: PMC11618242

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