Article
Mendelian Randomization Studies in Atopic Dermatitis: A Systematic Review.
The Journal of investigative dermatology - 1 May 2024
Elhage Kareem G, Kranyak Allison, Jin Joy Q, Haran Kathryn, Spencer Riley K, Smith Payton L, Davis Mitchell S, Hakimi Marwa, Bhutani Tina, Liao Wilson
Abstract excerpt
Prior studies have found associations between atopic dermatitis (AD) and comorbidities, including depression, obesity, asthma, and allergic rhinitis. Although observational studies often cannot establish robust causality between potential risk factors and AD, Mendelian randomization minimizes confounding when exploring causality by relying on random allelic assortment at birth. In this study, we systematically...
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