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Article

Unveiling the Role of Irisin as a Biomarker in Adolescent and Young Adult PCOS: A Metabolic and Hormonal Comparison of Hyperandrogenic and Normoandrogenic Phenotypes.

The journal of obstetrics and gynaecology research - 1 Apr 2026

Majeed Sadaf, Moin Hira, Fatima Sampana, Hashmi Fasih, Akhtar Tasneem, Shafi Riffat

Abstract excerpt

AIM: Polycystic ovary syndrome (PCOS) in adolescents and young adults is difficult to diagnose due to overlap with normal puberty. This study assessed irisin as a biomarker, comparing metabolic and hormonal profiles of hyperandrogenic (HA) and normoandrogenic (NA) phenotypes, determining an optimal cut-off, examining correlations with clinical markers, and identifying predictors of irisin levels. METHODS: A...

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Identifiers

PMID: 41968844
DOI: 10.1111/jog.70285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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