Article
Association of Vitamin D Receptor Gene Polymorphisms with Colorectal Cancer in a Saudi Arabian Population.
PloS one - 1 Jan 2016
Alkhayal Khayal A, Awadalia Zainab H, Vaali-Mohammed Mansoor-Ali, Al Obeed Omar A, Al Wesaimer Alanoud, Halwani Rabih, Zubaidi Ahmed M, Khan Zahid, Abdulla Maha-Hamadien
Abstract excerpt
BACKGROUND: Vitamin D, causally implicated in bone diseases and human malignancies, exerts its effects through binding to the vitamin D receptor (VDR). VDR is a transcription factor modulating the expression of several genes in different pathways. Genetic variants in the VDR gene have been associated with several cancers in different population including colorectal cancer. OBJECTIVE: To assess the association of...
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