Article
Start codon FokI and intron 8 BsmI variants in the vitamin D receptor gene and susceptibility to colorectal cancer.
Molecular biology reports - 1 Oct 2011
Mahmoudi Touraj, Karimi Khatoon, Mohebbi Seyed Reza, Fatemi Seyed Reza, Zali Mohammad Reza
Abstract excerpt
Epidemiological evidence suggests the protective effect of vitamin D against colorectal cancer (CRC) and the polymorphisms in vitamin D receptor (VDR) gene may influence the development of CRC. In this study the possible association of VDR FokI and BsmI gene polymorphisms with CRC risk was examined. A total of 904 subjects, including 452 cases with CRC and 452 controls were enrolled in this study. All 904...
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