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Article

Autophagy and LAP in the Fight against Fungal Infections: Regulation and Therapeutics

1 Jan 2018

Abstract excerpt

Phagocytes fight fungi using canonical and noncanonical, also called LC3-associated phagocytosis (LAP), autophagy pathways. However, the outcomes of autophagy/LAP in shaping host immune responses appear to greatly vary depending on fungal species and cell types. By allowing efficient pathogen clearance and/or degradation of inflammatory mediators, autophagy proteins play a broad role in cellular and immune...

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PMID: 29692681
DOI: 10.1155/2018/6195958

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