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Strategies Developed by Toxoplasma gondii to Survive in the Host

26 Apr 2019

Abstract excerpt

One of the most successful intracellular parasites, Toxoplasma gondii has developed several strategies to avoid destruction by the host. These include approaches such as rapid and efficient cell invasion to avoid phagocytic engulfment, negative regulation of the canonical CD40-CD40L-mediated autophagy pathway, impairment of the non-canonical IFN-γ-dependent autophagy pathway, and modulation of host cell survival...

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PMID: 31080445
DOI: 10.3389/fmicb.2019.00899

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