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Article

Foetal Microchimerism Correlates With Foetal-Maternal Histocompatibility Both During Pregnancy and Postpartum.

HLA - 1 Oct 2024

Staff Anne Cathrine, Fjeldstad Heidi E, Olsen Maria B, Øgaard Jonas, Viken Marte K, Kramer Cynthia S M, Eikmans Michael, Kroneis Thomas, Sallinger Katja, Kanaan Sami B, Sugulle Meryam, Jacobsen Daniel P

Abstract excerpt

Foetal cells are detectable in women decades postpartum, a state termed foetal microchimerism. The interplay between these semi-allogeneic foetal cells and the mother could be affected by genetic mismatches in the HLA loci. Here, we relate HLA allele and molecular mismatch values to the presence and quantity of foetal microchimerism in the maternal circulation during pregnancy and postpartum. A total of 76...

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PMID: 39435899
DOI: 10.1111/tan.15717

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