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Identification of Candidate Immunodominant Epitopes and Their HLA-Binding Prediction on BK Polyomavirus Proteins in Healthy Donors.

HLA - 1 Oct 2024

Lara-de-León Ana Gabriela, Mora-Buch Rut, Cantó Ester, Peña-Gómez Cleofé, Rudilla Francesc

Abstract excerpt

BK polyomavirus infection is an important cause of graft loss in transplant patients, however, currently available therapies lack effectiveness against this pathogen. Identification of immunological targets for potential treatments is therefore necessary. The aim of this study was to predict candidates of immunodominant epitopes within four BK virus proteins (VP1, VP2, VP3 and LTA) using PBMCs from 44 healthy...

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Identifiers

PMID: 39435889
DOI: 10.1111/tan.15722

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