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Article

Reduced Risk of BK Polyomavirus Infection in HLA-B51-positive Kidney Transplant Recipients.

Transplantation - 1 Mar 2019

Wunderink Herman F, Haasnoot Geert W, de Brouwer Caroline S, van Zwet Erik W, Kroes Aloysius C M, de Fijter Johan W, Rotmans Joris I, Claas Frans H J, Feltkamp Mariet C W

Abstract excerpt

BACKGROUND: Identification of specific HLA alleles and T-cell epitopes that influence the course of BK polyomavirus (BKPyV) infection after kidney transplantation (KTx), including development of BKPyV-associated nephropathy (BKPyVAN), can be useful for patient risk stratification and possibly vaccine development. METHODS: In a retrospective cohort of 407 living kidney donor-recipient pairs, donor and recipient...

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PMID: 30048396
DOI: 10.1097/TP.0000000000002376

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