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Article

Clinical-Scale Rapid Autologous BK Virus-Specific T Cell Line Generation From Kidney Transplant Recipients With Active Viremia for Adoptive Immunotherapy.

Transplantation - 1 Nov 2017

Lamarche Caroline, Orio Julie, Georges-Tobar Victoria, Pincez Thomas, Goupil Mathieu, Dahmani Amina, Carli Cedric, Brasey Ann, Busque Lambert, Delisle Jean-Sébastien

Abstract excerpt

BACKGROUND: Polyomavirus-associated nephropathy (PVAN) after BK virus reactivation in kidney transplant recipients (KTR) can compromise graft survival. Lowering immunosuppression is the only established approach to prevent or treat PVAN but nonspecifically increasing host immune competence also augments rejection risk. Ex vivo T cell stimulation/expansion offers the possibility to generate BK-specific T cell...

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PMID: 28230645
DOI: 10.1097/TP.0000000000001698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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