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Article

Six subphenotypes in septic shock: Latent class analysis of the PROWESS Shock study.

Journal of critical care - 1 Oct 2018

Gårdlund Bengt, Dmitrieva Natalia O, Pieper Carl F, Finfer Simon, Marshall John C, Taylor Thompson B

Abstract excerpt

PURPOSE: Septic shock is a highly heterogeneous condition which is part of the challenge in its diagnosis and treatment. In this study we aim to identify clinically relevant subphenotypes of septic shock using a novel statistic al approach. METHODS: Baseline patient data from a large global clinical trial of septic shock (n = 1696) was analysed using latent class analysis (LCA). This approach allowed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29933169
DOI: 10.1016/j.jcrc.2018.06.012
PMCID: PMC7416734

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