Article
Pre-operative circulating tumour DNA in high-risk primary cutaneous melanoma: prospective feasibility in molecular pathology.
Acta oncologica (Stockholm, Sweden) - 9 Sept 2026
Obinah Magnús Pétur Bjarnason, Høgdall Estrid, Poulsen Tim Svenstrup, Dreisig Karin, Litman Thomas, Johansen Christoffer, Bojesen Stig Egil, Hölmich Lisbet Rosenkrantz
Abstract excerpt
BACKGROUND AND PURPOSE: Circulating tumour DNA (ctDNA) has emerged as a prognostic biomarker in melanoma, but its detectability in pre-operative blood from patients presenting with primary cutaneous melanoma remains incompletely evaluated. We assessed the feasibility of pre-operative ctDNA detection in high-risk primary melanoma using routinely available methods in molecular pathology. PATIENTS/MATERIAL AND...
Read the complete abstract on PubMedTopics
- Humans
- Melanoma
- Circulating Tumor DNA
- Skin Neoplasms
- Prospective Studies
- Female