Association between ulcerative colitis and acute appendicitis - A Mendelian randomization study.

Abstract excerpt

Although the etiology of UC is not clear, some studies show that the appendix may be the starting point of UC, and the incidence of appendicitis is high in patients with UC. We performed a MR analysis to examine whether there is a potential causal relationship between UC and acute appendicitis. Our MR study revealed that the genetic liability of UC (OR, 0.9362; 95% CI 0.9014 - 0.9723; p = 0.00064) was associated...

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