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Article

No genetic causality between appendectomy and gastrointestinal cancers: a Mendelian randomization study and meta-analysis in European population.

Scientific reports - 29 Oct 2024

Wang Shuai, Zhang Tao, Sun Yuanlin, Yang Dongliang, Cao Xueyuan

Abstract excerpt

The impact of appendectomy on the risk of gastrointestinal cancers remains unknown. We aimed to systematically estimate the causal relationship between appendectomy and gastrointestinal cancers in the European population using two-sample Mendelian randomization (TSMR) study methods and meta-analysis. As part of the discovery cohort analysis, we identified independent genetic variants strongly associated with...

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Identifiers

PMID: 39472519
DOI: 10.1038/s41598-024-77600-6
PMCID: PMC11522438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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