Article
Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis.
Frontiers in immunology - 1 Jan 2022
Ricaño-Ponce Isis, Peeters Toon, Matzaraki Vasiliki, Houben Bert, Achten Ruth, Cools Peter, Netea Mihai G, Gyssens Inge C, Kumar Vinod
Abstract excerpt
Background: Acute appendicitis is one of the most common abdominal emergencies worldwide. Both environmental and genetic factors contribute to the disease. C-reactive protein (CRP) is an important biomarker in the diagnosis of acute appendicitis. CRP concentrations are significantly affected by genetic variation. However, whether such genetic variation is causally related to appendicitis risk remains unclear. In...
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