Follicular cell-derived thyroid carcinomas harboring novel genetic BRAFNON-V600E mutations: real-world data obtained using a multigene panel.

doi:10.20945/2359-4292-2024-0067

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Follicular cell-derived thyroid carcinomas harboring novel genetic BRAFNON-V600E mutations: real-world data obtained using a multigene panel.

Archives of endocrinology and metabolism - 1 Jan 2024

von Ammon Juliana Lima, Machado Gabriel Jeferson Rodríguez, da Matta Rafael Reis Campos, Telles Ana Clara, Carrijo Fabiane, Dos Santos Bruno Alexsander França, Brandão Juliana Cabral Duarte, da Silva Thiago Magalhães, Hecht Fabio, Colozza-Gama Gabriel Avela, Tezzei Julia Helena, Cerutti Janete Maria, Ramos Helton Estrela

Abstract excerpt

Objectives: To assess the molecular profile of follicular cell-derived thyroid carcinomas (FCDTCs) and correlate the identified mutations with the clinical and pathological features of the affected patients. Materials and methods: Cross-sectional study of tumor samples from 100 adult patients diagnosed with FCDTC between 2010 and 2019. The patients' clinical and pathological data were collected. Genomic DNA was...

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PMID: 39420942
DOI: 10.20945/2359-4292-2024-0067
PMCID: PMC11460960

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