Article
Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism - 1 Nov 2014
McFadden David G, Dias-Santagata Dora, Sadow Peter M, Lynch Kerry D, Lubitz Carrie, Donovan Samuel E, Zheng Zongli, Le Long, Iafrate A J, Daniels Gilbert H
Abstract excerpt
BACKGROUND: The diagnosis of the follicular variant of papillary thyroid carcinoma (FVPTC) is increasingly common. Recent studies have suggested that FVPTC is heterogeneous and comprises multiple tumor types with distinct biological behaviors and underlying genetics. OBJECTIVES: The purpose of this work was to identify the prevalence of mutations and gene fusions in known oncogenes in a panel representative of...
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