Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced expression of X-ray- and UV-induced chromosome aberrations by cytosine arabinoside in ataxia telangiectasia cells.

Mutation research - 1 Jan 2000

Ejima Y, Sasaki M S

Abstract excerpt

The effect of cytosine arabinoside (ara-C) on the frequency of X-ray- or UV-induced chromosome aberrations was studied in cultured skin fibroblasts derived from 2 normal persons, 4 ataxia telangiectasia (AT) patients and 2 obligate AT heterozygotes. Density-inhibited cells were irradiated with X-rays or UV, post-treated with ara-C, and chromosomes in the first post-irradiation mitoses were examined. UV, a poor...

Topics

Ataxia Telangiectasia
Cells, Cultured
Chromatids
Chromosome Aberrations
Chromosome Deletion
Cytarabine
DNA Repair
Humans
Mutation
Skin
Ultraviolet Rays
X-Rays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 3941661
DOI: 10.1016/0027-5107(86)90120-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3941661-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Enhanced expression of X-ray- and UV-induced chromosome aberrations by cytosine arabinoside in ataxia telangiectasia cells.PMID 3941661Read ↗

Lack of effect of inhibitors of DNA synthesis/repair on the ionizing radiation-induced chromosomal damage in G2 stage of ataxia telangiectasia cells.Semantic proximity Read ↗

Cytosine arabinoside enhancement of gamma irradiation induced mutations in human T-lymphocytes.Semantic proximity Read ↗

Reduced induction of P53 protein by gamma-irradiation in ataxia telangiectasia cells without constitutional mutations in exons 5, 6, 7, and 8 of the p53 gene.Semantic proximity Read ↗

Gene amplification in fibroblasts from ataxia telangiectasia (AT) patients and in X-ray hypersensitive AT-like Chinese hamster mutants.Semantic proximity Read ↗

A comparison of the roles of p53 mutation and AraC inhibition in the enhancement of bleomycin-induced chromatid aberrations in mouse and human cells.Semantic proximity Read ↗

ATM-Dependent and -Independent Gene Expression Changes in Response to Oxidative Stress, Gamma Irradiation, and UV IrradiationSemantic proximity Read ↗

Ataxia telangiectasia derived iPS cells show preserved x-ray sensitivity and decreased chromosomal instabilitySemantic proximity Read ↗

Parents of ataxia-telangiectasia patients display a distinct cellular immune phenotype mimicking ATM-mutated patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.