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Article

Monogenic Adult-Onset Inborn Errors of Immunity.

Frontiers in immunology - 1 Jan 2021

Staels Frederik, Collignon Tom, Betrains Albrecht, Gerbaux Margaux, Willemsen Mathijs, Humblet-Baron Stephanie, Liston Adrian, Vanderschueren Steven, Schrijvers Rik

Abstract excerpt

Inborn errors of immunity (IEI) are a heterogenous group of disorders driven by genetic defects that functionally impact the development and/or function of the innate and/or adaptive immune system. The majority of these disorders are thought to have polygenic background. However, the use of next-generation sequencing in patients with IEI has led to an increasing identification of monogenic causes, unravelling the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 34867986
DOI: 10.3389/fimmu.2021.753978
PMCID: PMC8635491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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