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Article

Development and validation of a prognostic model for endometrial carcinoma using causal genes identified by Mendelian randomization.

Medicine - 7 Nov 2025

Yang Dan, Li Yazhen, Xin Xiaoling, Ma Huilan

Abstract excerpt

Endometrial carcinoma (EC) remains an ambiguous pathogenesis. This study aimed to investigate the potential of causal genes in predicting EC prognosis. The prognostic biomarkers of EC were identified using univariate Cox regression analyses based on data from The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma (TCGA-UCEC). Mendelian randomization (MR) analyses were conducted to infer causal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41204543
DOI: 10.1097/MD.0000000000045769
PMCID: PMC12599766

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