Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL15RA-STAT3-GPX4/ACSL3 signaling leads to ferroptosis resistance in pancreatic cancer

12 Oct 2024

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease with a poor prognosis, and the lack of effective treatment methods accounts for its high mortality. Pancreatic stellate cells (PSCs) in the tumor microenvironment play an important role in the development of PDAC. Previous studies have reported that patients with PDAC are more vulnerable to ferroptosis inducers. To investigate the relationship...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39396119
DOI: 10.3724/abbs.2024153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL15RA-STAT3-GPX4/ACSL3 signaling leads to ferroptosis resistance in pancreatic cancerPMID 39396119Read ↗

Ferroptosis: New Strategies and Ideas for the Treatment of Pancreatic Ductal Adenocarcinoma.Semantic proximity Read ↗

Pancreatic Stellate Cells and the Targeted Therapeutic Strategies in Chronic PancreatitisSemantic proximity Read ↗

MGST1 facilitates novel KRASG12D inhibitor resistance in KRASG12D-mutated pancreatic ductal adenocarcinoma by inhibiting ferroptosis.Semantic proximity Read ↗

Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathwaySemantic proximity Read ↗

The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clustersSemantic proximity Read ↗

SLC38A5 Modulates Ferroptosis to Overcome Gemcitabine-Resistance in Pancreatic CancerSemantic proximity Read ↗

Alpha-Heredin targets CAMKⅡ/DRP1-Mediated mitochondrial fission to trigger ferroptosis in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Biology of pancreatic stellate cells—more than just pancreatic cancerSemantic proximity Read ↗

Simvastatin protects pancreatic cancer cells by promoting mitochondrial autophagy through TFEBSemantic proximity Read ↗

HSPA5 Regulates Ferroptotic Cell Death in Cancer CellsSemantic proximity Read ↗

Identification of key pathways and genes changes in pancreatic cancer cells (BXPC-3) after cross-talk with primary pancreatic stellate cells using bioinformatics analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.