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TRIM33 promotes glycolysis through regulating P53 K48-linked ubiquitination to promote esophageal squamous cell carcinoma growth

10 Oct 2024

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is a common fatal malignant tumor of the digestive tract; however, its pathogenic mechanism is unknown and lacks specific molecular diagnosis and treatment. Therefore, it is particularly important to identify new tumor biomarkers to enhance the early diagnosis and molecular-targeted therapy of ESCC. Here, we found that the E3 ubiquitin ligase Tripartitemotif-containing33...

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interferon and immune responses
Peptidase Inhibition and Analysis
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39389957
DOI: 10.1038/s41419-024-07137-z

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