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Article

Pancreatitis polygenic risk score is associated with acute pancreatitis in multifactorial chylomicronemia syndrome.

Journal of clinical lipidology - 1 Jan 2024

Guay Simon-Pierre, Paquette Martine, Taschereau Amélie, Desgagné Véronique, Bouchard Luigi, Bernard Sophie, Baass Alexis

Abstract excerpt

BACKGROUND: Multifactorial chylomicronemia syndrome (MCS) is a severe form of hypertriglyceridemia associated with an increased risk of acute pancreatitis (AP). The risk of AP is heterogenous and is associated with increased level of triglycerides (TG) and presence of rare variants in TG metabolism-related genes. OBJECTIVE: To determine if the accumulation of common variants in pancreatitis susceptibility genes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38443284
DOI: 10.1016/j.jacl.2024.02.007

Genes

TG
ABCG8
CLDN2
CTRB1
CTRC
PRSS1
PRSS2
SPINK1
TWIST2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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