Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid Evolution of Metastases in Patients with Treated G3 Neuroendocrine Tumors Associated with NEC-Like Transformation and TP53 Mutation.

Endocrine pathology - 1 Dec 2024

Kasajima Atsuko, Pfarr Nicole, Mayr Eva-Maria, Ura Ayako, Moser Elisa, von Werder Alexander, Agaimy Abbas, Pavel Marianne, Klöppel Günter

Abstract excerpt

Little is known about the morphomolecular features of G3 neuroendocrine tumors (G3NETs) under prolonged systemic treatments, although rapid progression is increasingly observed. This longitudinal study aims to elucidate the course and morphomolecular features of metastasized G3NETs with high-grade transformation. Clinical and histological findings in 40 patients with metastasized and treated G3NETs, which were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carcinoma, Neuroendocrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Longitudinal Studies

Share to Neoplasm Metastasis

Share to Neuroendocrine Tumors

Share to Pancreatic Neoplasms

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 39382626
DOI: 10.1007/s12022-024-09827-y
PMCID: PMC11659366

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid Evolution of Metastases in Patients with Treated G3 Neuroendocrine Tumors Associated with NEC-Like Transformation and TP53 Mutation.PMID 39382626Read ↗

Progression of low-grade neuroendocrine tumors (NET) to high-grade neuroendocrine neoplasms harboring the prototypical neuroendocrine carcinoma (NEC) co-alteration of RB1 and TP53.Semantic proximity Read ↗

Progression of Low-Grade Neuroendocrine Tumors (NET) to High-Grade Neoplasms Harboring the NEC-Like Co-alteration of RB1 and TP53Semantic proximity Read ↗

Concept of neuroendocrine neoplasms of all organs with a focus on grading, subtyping.Semantic proximity Read ↗

Histopathologic and genetic distinction of well-differentiated grade 3 neuroendocrine tumor versus poorly-differentiated neuroendocrine carcinoma in high-grade neuroendocrine neoplasms.Semantic proximity Read ↗

Neoplastic Progression in Neuroendocrine Neoplasms of the Pancreas.Semantic proximity Read ↗

The evolving landscape of neuroendocrine tumors.Semantic proximity Read ↗

High-grade transformation of pancreatic neuroendocrine tumor associated with TP53 mutations: A diagnostic pitfall mimicking neuroendocrine carcinoma.Semantic proximity Read ↗

Unraveling molecular pathways of poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: A systematic review.Semantic proximity Read ↗

Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms.Semantic proximity Read ↗

Esophageal neuroendocrine carcinoma: molecular insights, diagnostic advances, and emerging treatment strategies.Semantic proximity Read ↗

Digestive System Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms.Semantic proximity Read ↗

Genetics and Epigenetics of Gastroenteropancreatic Neuroendocrine NeoplasmsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.