Article
Mutational Landscape of Gastric Adenocarcinoma of the Fundic Gland Type Revealed by Whole Genome Sequencing.
Cancer medicine - 1 Oct 2024
Wei Hu, Chen Ze Min, Xue Xiu Fen, Xia Xi Li, Yang Gen Hua, Zhai Zhi Yong, Huang Zhao Yu, Zhou Ping, Bao Chong Ju, You Li Juan, Ou Yang Mei Ping, Xia Gui Li, Zeng Zhi Yu, Cui Xiao Bing, Pei Xiao Juan, Gong Wei
Abstract excerpt
BACKGROUND: Gastric adenocarcinoma of the fundic gland type (GA-FG) is a newly described variant of gastric adenocarcinoma with lack of knowledges regarding its genetic features. METHODS: We performed whole-genome sequencing (WGS) in formalin-fixed paraffin-embedded (FFPE) tumor tissues and matched adjacent noncancerous specimens from 21 patients with GA-FG, and integrated published datasets from 1105 patients...
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