Article
A Bidirectional Mendelian Randomization Study of the Causal Association Between Ischemic Stroke, Coronary Heart Disease, and Hydrocephalus.
Brain and behavior - 1 Oct 2024
Wang Wencai, Liu Menghao, Wang Zun, Ma Luyao, Zhao Yongqiang, Ye Wei, Li Xianfeng
Abstract excerpt
BACKGROUND: The association among coronary heart disease, ischemic stroke, and hydrocephalus remains ambiguous. OBJECTIVES: There is a need for a Mendelian randomization study to evaluate the underlying causality between coronary heart disease, ischemic stroke, and hydrocephalus. METHODS: The data source utilized genome-wide association studies, employing a threshold of p < 5 × 10-8 to identify single nucleotide...
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