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Article

Causal associations of osteoporosis with stroke: a bidirectional Mendelian randomization study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Dec 2024

Fan Zhengrui, Zhao Jie, Chen Jian, Hu Wei, Ma Jianxiong, Ma Xinlong

Abstract excerpt

This study employed bidirectional Mendelian randomization (MR) to investigate the causal relationship between osteoporosis (OP) and stroke. Utilizing large-scale genome-wide association data revealed a reciprocal relationship: stroke increases the risk of OP, and vice versa. These findings underscore the importance of addressing both conditions for comprehensive patient care. INTRODUCTION: The correlation between...

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Genome-Wide Association Study
Causality
Mendelian Randomization Analysis
Osteoporosis
Osteoporosis, Postmenopausal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Osteoporotic Fractures

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PMID: 39180677
DOI: 10.1007/s00198-024-07235-w

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