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Article

Antidepressants account for the causal effect of major depressive disorder on type 2 diabetes.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2025

Baranova Ancha, Liu Dongming, Sun Wenxi, Xu Chenxin, Chen Miao, Cao Hongbao, Zhang Fuquan

Abstract excerpt

BACKGROUND: Patients with major depressive disorder (MDD) face an elevated risk of type 2 diabetes (T2D). However, the contribution of the disease itself versus the side effects of antidepressants to this increased risk remains unclear. OBJECTIVE: This study aimed to investigate the overall and independent effects of MDD and exposure to antidepressants on T2D risk. METHODS: Summary genome-wide association study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39369807
DOI: 10.1016/j.pnpbp.2024.111164

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