Article
Limited evidence for classic selective sweeps in African populations.
Genetics - 1 Nov 2012
Granka Julie M, Henn Brenna M, Gignoux Christopher R, Kidd Jeffrey M, Bustamante Carlos D, Feldman Marcus W
Abstract excerpt
While hundreds of loci have been identified as reflecting strong-positive selection in human populations, connections between candidate loci and specific selective pressures often remain obscure. This study investigates broader patterns of selection in African populations, which are underrepresented despite their potential to offer key insights into human adaptation. We scan for hard selective sweeps using...
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