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Article

Effects of a bioengineered allogeneic cellular construct on burn-related macrophage phenotype.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 Jan 2000

Hernaez-Estrada Beatriz, Steele Lindsay A, Spiller Kara L

Abstract excerpt

Bioengineered allogeneic cellularised constructs (BACC) exert pro-healing effects in burn wounds and skew macrophage phenotype towards a predominately reparative phenotype. However, whether BACC can modulate the phenotype of dysregulated macrophages, like those present in burn wounds, is not known. To better understand the macrophage modulatory characteristics of the BACC, primary human macrophages were polarised...

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PMID: 39359182
DOI: 10.1111/wrr.13227

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