Article
PRKACB is a novel imprinted gene in marsupials.
Epigenetics & chromatin - 28 Sept 2024
Newman Trent, Bond Donna M, Ishihara Teruhito, Rizzoli Phoebe, Gouil Quentin, Hore Timothy A, Shaw Geoff, Renfree Marilyn B
Abstract excerpt
BACKGROUND: Genomic imprinting results in parent-of-origin-specific gene expression and, among vertebrates, is found only in therian mammals: marsupials and eutherians. A differentially methylated region (DMR), in which the methylation status of CpG dinucleotides differs between the two alleles, can mark the parental identity of imprinted genes. We developed a computational pipeline that detected CpG islands...
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