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Article

Association of polymorphisms of innate immunity-related genes and tuberculosis susceptibility in Mongolian population.

Human immunology - 1 Apr 2021

Han Jie, Ning Pengyuan, Ge An, Ma Xiaoxia, Alexander Burton Joshua, Yang Caiting, Cui Xiaogang, Wu Changxin, Hao Jinqi, Dong Li

Abstract excerpt

BACKGROUNDS: Genetic polymorphism of the toll-like receptor 2, 4 (TLR2, TLR4) and natural resistance-associated macrophage protein 1 (NRAMP1) genes may affect host immune response to Mycobacterium tuberculosis (Mtb) and lead to the variation of susceptibility to tuberculosis (TB) in humans. However, the association of single nucleotide polymorphisms (SNP) in these genes and the susceptibility to TB in Mongolian...

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PMID: 33692011
DOI: 10.1016/j.humimm.2021.02.008

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