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Evaluation of PAX1 / ST6GALNAC5 Methylation as a Triage Test for Cervical Intraepithelial Neoplasia and Cervical Couancer

1 Feb 2023

Abstract excerpt

Aim: To identify DNA methylation markers for triage in a cohort of human papillomavirus-positive (HPV+) women. Methods: The methylation markers were identified and evaluated for the detection of cervical high-grade squamous intraepithelial lesions (HSILs) or cervical cancer (collectively referred to as ‘HSIL+’) in HPV+ women (n = 692). Results: Combined PAX1/ST6GALNAC5 methylation testing yielded HSIL+...

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PMID: 37020401
DOI: 10.2217/epi-2022-0396

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