Histone deacetylase inhibitors: a potential epigenetic treatment for Duchenne muscular dystrophy.

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a life-threatening genetic disease that currently has no available cure. A number of pharmacological strategies that aim to target events downstream of the genetic defect are currently under clinical investigation, and some of these are outlined in this report. In particular, we focus on the ability of histone deacetylase inhibitors to promote muscle regeneration and prevent...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acetylation
• Share to Carbamates
• Share to Clinical Trials, Phase I as Topic