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Article

MEOX1 triggers myofibroblast apoptosis resistance, contributing to pulmonary fibrosis in mice

25 Sept 2024

Abstract excerpt

The apoptosis resistance of myofibroblasts is a hallmark in the irreversible progression of pulmonary fibrosis (PF). While the underlying molecular mechanism remains elusive. In this study, we unveiled a previously unrecognized mechanism underlying myofibroblast apoptosis resistance during PF. Our investigation revealed heightened expression of mesenchyme homeobox 1 (MEOX1) in the lungs of idiopathic pulmonary...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 39319990
DOI: 10.1002/jcp.31442

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