Article
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency.
Blood - 8 Sept 2011
Dickinson Rachel Emma, Griffin Helen, Bigley Venetia, Reynard Louise N, Hussain Rafiqul, Haniffa Muzlifah, Lakey Jeremy H, Rahman Thahira, Wang Xiao-Nong, McGovern Naomi, Pagan Sarah, Cookson Sharon, McDonald David, Chua Ignatius, Wallis Jonathan, Cant Andrew, Wright Michael, Keavney Bernard, Chinnery Patrick F, Loughlin John, Hambleton Sophie, Santibanez-Koref Mauro, Collin Matthew
Abstract excerpt
The human syndrome of dendritic cell, monocyte, B and natural killer lymphoid deficiency presents as a sporadic or autosomal dominant trait causing susceptibility to mycobacterial and other infections, predisposition to myelodysplasia and leukemia, and, in some cases, pulmonary alveolar proteinos...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.