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CRISPR/Cas12a-Triggered Visible-Light-Driven Photoelectrochemical Assay with Single-Nucleotide Resolution for Drug-Resistant Foodborne Salmonella Detection.

Journal of agricultural and food chemistry - 2 Oct 2024

Li Jun, Song Jiaen, Chen Yanbai, Zhao Zhifeng, Wang Song, Deng Yi, Lai Shuangquan, Yang Hao

Abstract excerpt

The prevalence of foodborne pathogenic bacteria, especially drug-resistant strains, such as Salmonella enterica, poses serious threats to public health, highlighting the requirement for the development of rapid and precise detection methods. Herein, a CRISPR/Cas12a-triggered visible-light-driven photoelectrochemical (PEC) assay (CasPEC) was developed using a SiO2-quenched BiVO4/MoS2 p/n-type heterojunction as the...

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PMID: 39298407
DOI: 10.1021/acs.jafc.4c05993

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