Colorimetric CRISPR Biosensor: A Case Study with Salmonella Typhi

Abstract excerpt

There is a critical need to implement a sensitive and specific point-of-care (POC) biosensor that addresses the instrument limitations and manufacturing challenges faced in resource-constrained contexts. In this paper we focus on enteric fever which is a highly contagious and prevalent infection in low- and middle-income countries. Although easily treatable, its ambiguous symptoms paired with a lack of fast, accur...

Topics

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• Communicable Diseases
• CRISPR and Genetic Engineering
• CRISPR-Cas Systems
• Genetic Diseases, Inborn
• Nucleic Acid Amplification Techniques
• Nucleic Acids
• Point-of-Care Systems
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

3a3d1c86-c264-5e2b-8979-9e8b644741df

DOI

10.1101/2024.08.05.606709