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Article

Parsimonious immune-response endotypes and global outcome in patients with traumatic brain injury.

EBioMedicine - 1 Oct 2024

Samanta Romit J, Chiollaz Anne-Cécile, Needham Edward, Yue John K, Helmy Adel, Zanier Elisa R, Wang Kevin K W, Kobeissy Firas, Posti Jussi P, Summers Charlotte, Manley Geoffrey T, Maas Andrew Ir, Tenovuo Olli, Sanchez Jean-Charles, Menon David K

Abstract excerpt

BACKGROUND: The inflammatory response in patients with traumatic brain injury (TBI) offers opportunities for stratification and intervention. Previous unselected approaches to immunomodulation in patients with TBI have not improved patient outcomes. METHODS: Serum and plasma samples from two prospective, multi-centre observational studies of patients with TBI were used to discover (Collaborative European...

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Identifiers

PMID: 39293212
DOI: 10.1016/j.ebiom.2024.105310
PMCID: PMC11424973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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