Article
Sleep Disorder Phenotypes and the Risk of Incident Heart Failure: A meta-analysis with Mendelian randomization validation.
Saudi medical journal - 1 Mar 2026
Yan Fang, Fan Lihua, Chen Yunhu
Abstract excerpt
Objectives: To quantify how specific sleep-disorder phenotypes are related to incident heart failure (HF) using a meta-analysis of cohort data and to probe causal relevance via 2-sample Mendelian randomization (MR). Methods: Fourteen cohorts comprised of participants without HF at baseline were p...
Topics
- Humans
- Heart Failure
- Phenotype
- Mendelian Randomization Analysis
- Sleep Wake Disorders
- Sleep Apnea, Obstructive
- Incidence
