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Article

Sleep Disorder Phenotypes and the Risk of Incident Heart Failure: A meta-analysis with Mendelian randomization validation.

Saudi medical journal - 1 Mar 2026

Yan Fang, Fan Lihua, Chen Yunhu

Abstract excerpt

Objectives: To quantify how specific sleep-disorder phenotypes are related to incident heart failure (HF) using a meta-analysis of cohort data and to probe causal relevance via 2-sample Mendelian randomization (MR). Methods: Fourteen cohorts comprised of participants without HF at baseline were pooled (49,501 exposed; 337,317 controls). A random effects meta-analysis produced pooled hazard ratios (HRs) with 95%...

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Identifiers

PMID: 42238282
DOI: 10.15537/1658-3175.1035
PMCID: PMC13227396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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